IONSIonis PharmaceuticalsHealth Care
$61.05EarningsNov 4, 2026
1D—1W—1M—3M—1Y—
Market cap$10.1BCompany infoRevenue$873.8M52-wk range$42 – $87IndustryBiotechnologyWebsiteionispharma.comRelated—
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▲ +40.6% · 1YSPY
Weekly rank vs S&P 500 · 52wk
Not enough history to plot
ValuationHow the price is priced — vs cohort and vs its own past
MetricValueUnivSect5-yr range
P / E———
P / S11.6×710
6
15
P / FCF———
EV / EBITDA2.4×9699
3
275
P / E (fwd)———
ProfitabilityMargins and returns on capital
MetricValueUnivSect5-yr range
Gross margin98.2%9998
98%
99%
Operating margin-68.1%15
-90%
2%
Net margin-64.6%15
-90%
1%
ROE-105.8%13
-107%
1%
ROIC-18.1%28
-22%
1%
Financial healthLeverage and liquidity
MetricValueUnivSect5-yr range
Debt / equity4.9044
1.6
5.7
Net debt / EBITDA0.0×7267
Current ratio7.889697
Interest coverage-8.3×37
Per shareTTM, with year-over-year change
Revenue / share$5.28▼ −7%
EPS (diluted)$-3.46▼ −86%
FCF / share$-3.38▼ −91%
Est. EPS growth (fwd)—