IONSIonis PharmaceuticalsHealth Care
$76.50EarningsAug 5, 2026
1D—1W—1M—3M—1Y—
Market cap$12.6BCompany infoRevenue$1.1B52-wk range$40 – $87IndustryBiotechnologyWebsiteionispharma.comRelated—
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▲ +93.0% · 1YSPY
Weekly rank vs S&P 500 · 52wk
Not enough history to plot
ValuationHow the price is priced — vs cohort and vs its own past
MetricValueUnivSect5-yr range
P / E———
P / S11.9×76
6
14
P / FCF———
EV / EBITDA2.7×9699
3
275
P / E (fwd)———
ProfitabilityMargins and returns on capital
MetricValueUnivSect5-yr range
Gross margin98.4%9999
98%
99%
Operating margin-33.4%25
-90%
2%
Net margin-30.9%38
-90%
1%
ROE-60.4%26
-107%
1%
ROIC-12.3%310
-22%
1%
Financial healthLeverage and liquidity
MetricValueUnivSect5-yr range
Debt / equity3.6364
1.3
5.7
Net debt / EBITDA-0.0×7267
Current ratio4.109082
Interest coverage-4.4×48
Per shareTTM, with year-over-year change
Revenue / share$6.42▲ +47%
EPS (diluted)$-2.09▲ +30%
FCF / share$-5.89▼ −71%
Est. EPS growth (fwd)—