Health Care Stocks That Beat the S&P 500 Most Consistently

Steady sector leaders, not one-month wonders

Updated August 30, 2026

Sector rotation makes raw-return lists whiplash — a sector’s whole cohort looks brilliant in its quarter and terrible after. Weekly consistency cuts through that: it asks which Health Care names finished ahead of the index week after week, through their sector’s good stretches and bad ones. For scale: the typical Health Care stock managed 25 winning weeks of 52.

#StockWeeks > SPY1Y excess1Y return1M
1CRLCharles River Laboratories32 / 52+57.0%+79.1%+24.2%
Beat the S&P 500 in 32 of its last 52 weeks, on a +79.1% total return — +57.0% ahead of the index for the year.
2BIIBBiogen30 / 52+31.7%+60.2%+5.1%
Beat the S&P 500 in 30 of its last 52 weeks, on a +60.2% total return — +31.7% ahead of the index for the year.
3HUMHumana30 / 52+27.2%+29.7%+5.1%
Beat the S&P 500 in 30 of its last 52 weeks, on a +29.7% total return — +27.2% ahead of the index for the year.
4CNCCentene Corporation29 / 52+76.9%+124.5%+6.4%
Beat the S&P 500 in 29 of its last 52 weeks, on a +124.5% total return — +76.9% ahead of the index for the year.
5VTRSViatris29 / 52+29.2%+56.8%−8.0%
Beat the S&P 500 in 29 of its last 52 weeks, on a +56.8% total return — +29.2% ahead of the index for the year.
6WSTWest Pharmaceutical Services29 / 52+17.4%+37.2%−0.6%
Beat the S&P 500 in 29 of its last 52 weeks, on a +37.2% total return — +17.4% ahead of the index for the year.
7MCKMcKesson Corporation29 / 52+13.4%+30.7%+3.2%
Beat the S&P 500 in 29 of its last 52 weeks, on a +30.7% total return — +13.4% ahead of the index for the year.
8LLYLilly (Eli)28 / 52+38.7%+59.8%+1.5%
Beat the S&P 500 in 28 of its last 52 weeks, on a +59.8% total return — +38.7% ahead of the index for the year.
9WATWaters Corporation28 / 52+23.7%+40.7%+9.0%
Beat the S&P 500 in 28 of its last 52 weeks, on a +40.7% total return — +23.7% ahead of the index for the year.
10DGXQuest Diagnostics28 / 52+14.3%+35.0%+3.6%
Beat the S&P 500 in 28 of its last 52 weeks, on a +35.0% total return — +14.3% ahead of the index for the year.
11DXCMDexcom28 / 52−0.0%+18.9%+21.8%
Beat the S&P 500 in 28 of its last 52 weeks, on a +18.9% total return — −0.0% ahead of the index for the year.
12JNJJohnson & Johnson27 / 52+25.4%+51.6%+4.8%
Beat the S&P 500 in 27 of its last 52 weeks, on a +51.6% total return — +25.4% ahead of the index for the year.
13CVSCVS Health27 / 52+16.9%+29.4%−11.6%
Beat the S&P 500 in 27 of its last 52 weeks, on a +29.4% total return — +16.9% ahead of the index for the year.
14VRTXVertex Pharmaceuticals27 / 52+16.5%+39.2%+12.5%
Beat the S&P 500 in 27 of its last 52 weeks, on a +39.2% total return — +16.5% ahead of the index for the year.
15ELVElevance Health27 / 52+11.4%+27.3%+4.8%
Beat the S&P 500 in 27 of its last 52 weeks, on a +27.3% total return — +11.4% ahead of the index for the year.
16ABBVAbbVie27 / 52+5.6%+22.8%−0.8%
Beat the S&P 500 in 27 of its last 52 weeks, on a +22.8% total return — +5.6% ahead of the index for the year.
17CORCencora27 / 52−5.7%+10.8%+3.1%
Beat the S&P 500 in 27 of its last 52 weeks, on a +10.8% total return — −5.7% ahead of the index for the year.
18MRNAModerna26 / 52+215.4%+449.8%+138.2%
Beat the S&P 500 in 26 of its last 52 weeks, on a +449.8% total return — +215.4% ahead of the index for the year.
19RVTYRevvity26 / 52+23.2%+45.4%+13.4%
Beat the S&P 500 in 26 of its last 52 weeks, on a +45.4% total return — +23.2% ahead of the index for the year.
20REGNRegeneron Pharmaceuticals26 / 52+18.7%+35.3%+7.6%
Beat the S&P 500 in 26 of its last 52 weeks, on a +35.3% total return — +18.7% ahead of the index for the year.

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