Health Care Stocks That Beat the S&P 500 Most Consistently

Steady sector leaders, not one-month wonders

Updated October 13, 2026

Sector rotation makes raw-return lists whiplash — a sector’s whole cohort looks brilliant in its quarter and terrible after. Weekly consistency cuts through that: it asks which Health Care names finished ahead of the index week after week, through their sector’s good stretches and bad ones. For scale: the typical Health Care stock managed 25 winning weeks of 52.

#StockWeeks > SPY1Y excess1Y return1M
1CRLCharles River Laboratories32 / 52+69.0%+79.0%+9.5%
Beat the S&P 500 in 32 of its last 52 weeks, on a +79.0% total return — +69.0% ahead of the index for the year.
2HUMHumana32 / 52+52.0%+49.9%+3.2%
Beat the S&P 500 in 32 of its last 52 weeks, on a +49.9% total return — +52.0% ahead of the index for the year.
3BIIBBiogen31 / 52+38.3%+56.2%+5.3%
Beat the S&P 500 in 31 of its last 52 weeks, on a +56.2% total return — +38.3% ahead of the index for the year.
4MRNAModerna30 / 52+272.3%+706.0%+47.4%
Beat the S&P 500 in 30 of its last 52 weeks, on a +706.0% total return — +272.3% ahead of the index for the year.
5CNCCentene Corporation30 / 52+60.5%+92.6%−0.8%
Beat the S&P 500 in 30 of its last 52 weeks, on a +92.6% total return — +60.5% ahead of the index for the year.
6VTRSViatris30 / 52+48.0%+77.1%+3.5%
Beat the S&P 500 in 30 of its last 52 weeks, on a +77.1% total return — +48.0% ahead of the index for the year.
7WSTWest Pharmaceutical Services30 / 52+22.4%+42.0%+4.7%
Beat the S&P 500 in 30 of its last 52 weeks, on a +42.0% total return — +22.4% ahead of the index for the year.
8MCKMcKesson Corporation30 / 52+9.6%+26.0%+5.6%
Beat the S&P 500 in 30 of its last 52 weeks, on a +26.0% total return — +9.6% ahead of the index for the year.
9RVTYRevvity28 / 52+52.1%+75.6%+20.7%
Beat the S&P 500 in 28 of its last 52 weeks, on a +75.6% total return — +52.1% ahead of the index for the year.
10MRKMerck & Co.28 / 52+50.4%+65.1%−2.0%
Beat the S&P 500 in 28 of its last 52 weeks, on a +65.1% total return — +50.4% ahead of the index for the year.
11LLYLilly (Eli)28 / 52+37.9%+40.0%+2.5%
Beat the S&P 500 in 28 of its last 52 weeks, on a +40.0% total return — +37.9% ahead of the index for the year.
12WATWaters Corporation28 / 52+30.4%+29.7%+4.7%
Beat the S&P 500 in 28 of its last 52 weeks, on a +29.7% total return — +30.4% ahead of the index for the year.
13AMGNAmgen28 / 52+30.2%+42.3%+8.2%
Beat the S&P 500 in 28 of its last 52 weeks, on a +42.3% total return — +30.2% ahead of the index for the year.
14TMOThermo Fisher Scientific28 / 52+24.8%+26.3%+8.1%
Beat the S&P 500 in 28 of its last 52 weeks, on a +26.3% total return — +24.8% ahead of the index for the year.
15JNJJohnson & Johnson28 / 52+23.3%+30.4%−6.6%
Beat the S&P 500 in 28 of its last 52 weeks, on a +30.4% total return — +23.3% ahead of the index for the year.
16CORCencora28 / 52−7.9%+3.8%+1.2%
Beat the S&P 500 in 28 of its last 52 weeks, on a +3.8% total return — −7.9% ahead of the index for the year.
17IQVIQVIA27 / 52+29.5%+31.6%−1.9%
Beat the S&P 500 in 27 of its last 52 weeks, on a +31.6% total return — +29.5% ahead of the index for the year.
18MTDMettler Toledo27 / 52+17.3%+25.5%+24.3%
Beat the S&P 500 in 27 of its last 52 weeks, on a +25.5% total return — +17.3% ahead of the index for the year.
19DXCMDexcom27 / 52+15.5%+30.6%+0.4%
Beat the S&P 500 in 27 of its last 52 weeks, on a +30.6% total return — +15.5% ahead of the index for the year.
20VRTXVertex Pharmaceuticals27 / 52+11.4%+19.0%−6.6%
Beat the S&P 500 in 27 of its last 52 weeks, on a +19.0% total return — +11.4% ahead of the index for the year.

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